OC Feet News
Posts for: August, 2018
Lunula Laser® is the revolutionary low-level laser therapy bringing new hope to people suffering from the painful, discolored and disfigured toenails associated with onychomycosis, or nail fungus. Unlike other treatments, Lunula Laser® promises no pain, no risk and no downtime and is the easy, convenient way to experience healthy, clear nails again.
The Lunula Laser® laser targets fungus that lives in and under the toenail. The laser light passes through the nail without causing damage to it or the surrounding skin. Effective, the Lunula Laser® poses none of the risk and harmful side effects of oral anti-fungal medications. Plus, this convenient in-office procedure typically takes only minutes to perform, with absolutely no recovery time required. In fact, as little as four 12-minute sessions are needed to treat the affected area.
Stop suffering the pain and embarrassment of unsightly nail fungus, and enjoy clear, beautiful nails today.
ADVANTAGES OF THE LUNULA LASER:
- No pain, no downtime and no risk
- Avg. 6.1 clearance at 6 months
- No dangerous smoke plumes
- Unattended procedure
- 89% of patients respond
- Made in the USA
HISTOLOGY – LUNULA MECHANISM OF ACTION
LunulaLaser is a dual-diode, low-level laser device that delivers a multifaceted treatment of onychomycosis (OM) Lunulalaser follows the principles of photochemistry, a science that explores light’s effect cell function and behavior. The photochemical mechanism enables Lunulalaser to give a direct, non-contact treatment that produces no macroscopic sensation: no heating, tingling, burning. The mechanism of photochemistry is likened to the agonist effect of a drug, which describes the use of a certain molecule to start a secondary cascade. Laser therapy uses photonic energy to modulate secondary cellular reactions without the patient feeling the device working.
LunulaLaser impressive clinical response stems from its two therapeutic wavelengths: 405 nm (violet) and 635 nm (red). Each wavelength performs a very specific function to provide a comprehensive treatment of OM. The manner in which the wavelengths are delivered represents an innovative and proprietary feature of LunulaLaser. Lunula administers the laser as a line-generated beam, which maximizes the treatment surface area. The fungal pathogen may not only affect multiple toes, but also may be found deep within a dystrophic nail or along the nail bed and root. The line-generated beam ensures that, regardless of where the fungal pathogen resides, an effective treatment will be administered.
Violet has been demonstrated to have an antimicrobial effect by upregulating the production of ROS, leading to the generation of hydrogen peroxide, hypochlorous acid and droxyl radicals. When applied concurrently, the combined antimicrobial and biostimulative effects appear to provide a therapeutically beneficial combination, as demonstrated by the mean percent changes in clarity. A potential phototarget for the 405 nm wavelength is also a system responsible for catalyzing the generation of ROS, nicotinamide adenine dinucleotide phosphate oxidase (NOX). NOX transfers electrons from cytosolic NADPH to flavin adenine dinucleotide (FAD), then to extracellular molecular oxygen to generate superoxide. The third and fifth transmembrane domains of NOX bind two prosthetic heme groups that shuttle electrons from FAD to oxygen. It has been suggested that the prosthetic heme, which has been recognized as a photosensitizer, responds to the delivery of blue light. Stimulation of NOX could potentially provide two benefits: first, phagocytes are activated, and second, dermatophytes are susceptible to the toxic effects of ROS.
COMBINATION OF 635nm AND 405nm
eNOS→Nitric Oxide (NO)
Cytochrome c oxidase→Reactive Oxygen Species (ROS)